Who Gets Pediatric Localized Scleroderma?

Localized scleroderma (LS) is rare. About 50 out of every 100,000 children in the United States likely have LS, and about 1 to 3 out of every 100,000 children develop LS each year.

Juvenile LS (jLS) is slightly more common in girls than in boys. Usually, this disease appears between ages 6 to 8.

  • Kills infected cells
  • Lowers or raises inflammation
  • Makes antibodies and other cells

Localized scleroderma (LS) is more common in children than adults. Children with LS typically have the linear subtype (see below). Juvenile LS is more common in white children. Compared to other similar conditions in one North American data bank of about 10,000 children:

  • jLS is 17 times less common than juvenile idiopathic arthritis (JIA)
  • jLS is 2-3 times less common than lupus
  • jLS is 6-10 times more common than juvenile systemic sclerosis
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